St Michael's Hospital, 30 Bond Street, Toronto, ON M5B 1W8 | info@odprn.ca

The Burden of Premature Opioid-Related Mortality

The ODPRN conducted a serial cross-sectional study of all opioid-related deaths in Ontario, Canada between January 1, 1991 and December 31, 2010 to examine the rate and to estimate the years of potential life lost (YLL) due to opioid-related mortality.  Additional analyses examining specific opioids involved in opioid overdose deaths as well as patients characterisitics were further explored.

Key findings demonstrate:

  • The overall rate of opioid-related morality increased by 242% between 1991 and 2010
  • The annual YLL due to premature opioid related death increased 3-fold
  • The proportion of deaths attributable to opioids increased significantly over time among all ages
  • By 2010, nearly 1 of every 8 deaths among individuals aged 25 to 34 years was opioid-related
  • Tha majority of opioid-related deaths occurred in men, involved a single opioid, and were deemed accidental
  • The opioids most commonly involved in opioid-related deaths were morphine and heroin (or the two combined), followed by oxycodone, methadone and codeine.
  • Oxycodone was the opioid most commonly involved in overdose deaths involving a single opioid
  • For overdose deaths where multiple opioids were involved, the most commonly involved opioids were codeine, morphine or heroin (or both)

To view a copy of the published manuscript click on the following link:
The Burden of Premature Opioid-Related Mortality

To view a copy of the report, click on the following link:
Opioid Related Deaths in Ontario between 1991  and 2010

In the map illustrated below, we report the annualized rates of opioid-related deaths, by County in Ontario using the most recent 5 years of data (2006-2010).


Download a Summary of the Project:

Research Minute - PYLL -Physician FINAL Research Minute - PYLL- Patient FINAL Research Minute - PYLL - Policy FINAL
Clinician Research Minute Patient Research Minute Policy Research Minute
St Michael's Hospital, 30 Bond Street, Toronto, ON M5B 1W8 | info@odprn.ca